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Coronavirus?? We gone?

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Post by WhiteBoyHatcher on 2020-09-02, 21:31

Good deal Dro.

I watched an IG post from Dwayne Johnson today. I typically don't watch his stuff unless he's clowning on Kevin Hart. But today I did. He and his wife and twin little girls all had the rona. Kind of scary, he said they were being very careful in quarantine and recently started seeing only very close friends who they also know were being safe. But their close friends had gotten it somewhere, they still didn't know where, were completely asymptomatic and passed out to his whole family. Said the other family was devastated. He said his girls got mild sore throats for a couple of days but were mostly fine. However it was a bear for him and his wife. They are through it now, but if it can knock The Rock on his ass....

Also scary how they caught it. We are doing stuff like that, 99% outdoors, so the kids can play with friends. We feel it's necessary for them. We stay distanced from the adults. But yeah it's for sure a risk. And I don't know how much longer we can do stuff outside because our winter lasts 9.5 months.
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Post by MiamiSpartan on 2020-09-02, 21:33

Dendrobates wrote:
Watch Out Pylon! wrote:Shit Dendro. Hope all is well.

Our kiddo got sick about a month ago. Wasn't bad for her but my wife got it and she got real sick. Got tested and came back negative. Pulled the kid from daycare permanently after that. For other reasons as well. Let's just say we've been leery about how seriously our daycare was taking all of this. Sucks too because other than this they've been great. But this is a huge issue and they're really dropping the ball in our opinion.

Anyway, we're both working from home and trying to give her pre-preschool lessons and keep her entertained long enough to get actual work done. It's a fucking chore.

Yikes. I’m glad it was all negative. I wanted to do preschool, but we said we’re not doing it. We will re-evaluate it in January, but I’m sure it will be worse then. However, if it changes it changes.

Btw... daughters test was negative and she’s feeling better. So all good here.

Great to hear!!
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Post by Dendrobates on 2020-09-03, 08:06

WhiteBoyHatcher wrote:Good deal Dro.

I watched an IG post from Dwayne Johnson today. I typically don't watch his stuff unless he's clowning on Kevin Hart. But today I did. He and his wife and twin little girls all had the rona. Kind of scary, he said they were being very careful in quarantine and recently started seeing only very close friends who they also know were being safe. But their close friends had gotten it somewhere, they still didn't know where, were completely asymptomatic and passed out to his whole family. Said the other family was devastated. He said his girls got mild sore throats for a couple of days but were mostly fine. However it was a bear for him and his wife. They are through it now, but if it can knock The Rock on his ass....

Also scary how they caught it. We are doing stuff like that, 99% outdoors, so the kids can play with friends. We feel it's necessary for them. We stay distanced from the adults. But yeah it's for sure a risk. And I don't know how much longer we can do stuff outside because our winter lasts 9.5 months.

That's what we're doing too. I avoid restaurants and go into stores (always masked) when I have to. And we let our daughter play with only certain people and close family. I know it's not perfect. There is risk. I am trying to assess what activities we can do to have some normalcy, while minimizing the risk. I assumed my daughter got some bug from playing with some family kids. No one else got sick. Her immune system hasn't been challenged in a while either.
We did go to the Detroit zoo last week. And while it's possible she got it there, I didn't think so. I thought their setup was awesome. You have a scheduled time, masks inn inside areas and up close to exhibits, with very few people around. It was the least amount of people I've ever seen there, and it was great.

It's definitely tough trying to navigate the best for a growing developing kid, and lowering their risk of infection. Winter will be very very tough, assuming this shit is a lot worse. Im going to lose my mind being stuck inside for so long.
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Post by Jake from State Farm on 2020-09-03, 08:24

Dendrobates wrote:
WhiteBoyHatcher wrote:Good deal Dro.

I watched an IG post from Dwayne Johnson today. I typically don't watch his stuff unless he's clowning on Kevin Hart. But today I did. He and his wife and twin little girls all had the rona. Kind of scary, he said they were being very careful in quarantine and recently started seeing only very close friends who they also know were being safe. But their close friends had gotten it somewhere, they still didn't know where, were completely asymptomatic and passed out to his whole family. Said the other family was devastated. He said his girls got mild sore throats for a couple of days but were mostly fine. However it was a bear for him and his wife. They are through it now, but if it can knock The Rock on his ass....

Also scary how they caught it. We are doing stuff like that, 99% outdoors, so the kids can play with friends. We feel it's necessary for them. We stay distanced from the adults. But yeah it's for sure a risk. And I don't know how much longer we can do stuff outside because our winter lasts 9.5 months.

That's what we're doing too. I avoid restaurants and go into stores (always masked) when I have to. And we let our daughter play with only certain people and close family. I know it's not perfect.  There is risk. I am trying to assess what activities we can do to have some normalcy,  while minimizing the risk. I assumed my daughter got some bug from playing with some family kids. No one else got sick. Her immune system hasn't been challenged in a while either.
We did go to the Detroit zoo last week. And while it's possible she got it there, I didn't think so. I thought their setup was awesome.  You have a scheduled time, masks inn inside areas and up close to exhibits,  with very few people around. It was the least amount of people I've ever seen there, and it was great.

It's definitely tough trying to navigate the best for a growing developing kid, and lowering their risk of infection. Winter will be very very tough,  assuming this shit is a lot worse. Im going to lose my mind being stuck inside for so long.

It is tough. My sister in law's grandaughters went to school, they live in Florida, and both came home with a fever. Turned out to be nothing more than what kids pass around in school every day. My son and daughter in law decided to keep my grandaughter home instead of starting her in kindergarten this year and homeschool. Daughter in law had breast cancer recently and doesn't need her bringing home any surprises from school with her having a compromised immune system.
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Post by steveschneider on 2020-09-03, 10:45

The Rock coming forward about his families experience with Covid could save a lot of lives. His message will probably reach the crowd that needs to hear it the most.
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Post by Motown Spartan on 2020-09-03, 11:13

steveschneider wrote:The Rock coming forward about his families experience with Covid could save a lot of lives. His message will probably reach the crowd that needs to hear it the most.

The Pantry?
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Post by Robert J Sakimano on 2020-09-03, 11:24

steveschneider wrote:The Rock coming forward about his families experience with Covid could save a lot of lives. His message will probably reach the crowd that needs to hear it the most.
I don't think anyone can get through to the stupid people who trust jesus over science.

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Post by Floyd Robertson on 2020-09-03, 19:29

kInKy

[tw]1301663293795373058[/tw]
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Post by MiamiSpartan on 2020-09-03, 19:33

Floyd Robertson wrote:kInKy

[tw]1301663293795373058[/tw]


Wait, that's not standard for a girl to ask that of me?
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Post by DWags on 2020-09-03, 20:52

“You cant eat ass with a mask on”.
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Post by MiamiSpartan on 2020-09-04, 08:30

So the new Batman has the bat disease (covid).
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Post by duffy munn on 2020-09-04, 08:51

MiamiSpartan wrote:So the new Batman has the bat disease (covid).

What's next? Robin will get the bird flu?
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Post by Robert J Sakimano on 2020-09-04, 08:56

duffy munn wrote:
MiamiSpartan wrote:So the new Batman has the bat disease (covid).  

What's next? Robin will get the bird flu?
you should tweet that.
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Post by DWags on 2020-09-04, 09:08

I've been going back and forth with my fear of this. I just heard the White House is now projecting up to 400K dead by Jan. 1. By December we will be hitting 3000 a day. That's from the White house's own model. I also have to make a living which requires me to meet at least 20 people a day. It's only me and my wife at home now, and I always use hand sanittizer and wear masks out in public. I really do believe that by listening to some t.v. stations there is a "fear porn" factor going on, but I also am taken aback by numbers I see. I guess I'm just confused about this, and I go back and forth with levels of fear. This sucks.
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Post by duffy munn on 2020-09-04, 09:18

Robert J Sakimano wrote:
duffy munn wrote:

What's next? Robin will get the bird flu?
you should tweet that.

Someone will need to teach me how to twitters
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Post by Robert J Sakimano on 2020-09-04, 10:00

DWags wrote:I've been going back and forth with my fear of this. I just heard the White House is now projecting up to 400K dead by Jan. 1. By December we will be hitting 3000 a day. That's from the White house's own model. I also have to make a living which requires me to meet at least 20 people a day. It's only me and my wife at home now, and I always use hand sanittizer and wear masks out in public. I really do believe that by listening to some t.v. stations there is a "fear porn" factor going on, but I also am taken aback by numbers I see. I guess I'm just confused about this, and I go back and forth with levels of fear. This sucks.
the blame for this lies squrely in the massive failure iin the White House dating back to January and still going on today. They genuinely do not care that 190,000 Americans are dead, many more sick never to fully recover, families are destroyed, businesses and life savings are gone.

They. Do. Not. Care.

in fact, the cruelty and needless death and despair is all part of the plan.


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Post by Dendrobates on 2020-09-04, 10:02

DWags wrote:I've been going back and forth with my fear of this. I just heard the White House is now projecting up to 400K dead by Jan. 1. By December we will be hitting 3000 a day. That's from the White house's own model. I also have to make a living which requires me to meet at least 20 people a day. It's only me and my wife at home now, and I always use hand sanittizer and wear masks out in public. I really do believe that by listening to some t.v. stations there is a "fear porn" factor going on, but I also am taken aback by numbers I see. I guess I'm just confused about this, and I go back and forth with levels of fear. This sucks.

I hear yea wags.

Winter is coming. And it’s gonna suck.
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Post by MiamiSpartan on 2020-09-04, 11:48

DWags wrote:I've been going back and forth with my fear of this. I just heard the White House is now projecting up to 400K dead by Jan. 1. By December we will be hitting 3000 a day. That's from the White house's own model. I also have to make a living which requires me to meet at least 20 people a day. It's only me and my wife at home now, and I always use hand sanittizer and wear masks out in public. I really do believe that by listening to some t.v. stations there is a "fear porn" factor going on, but I also am taken aback by numbers I see. I guess I'm just confused about this, and I go back and forth with levels of fear. This sucks.


FWIW, it's not the White House's model, it's from the University of Washington, but is the organization whose models the White House would use and cite early on. I don't think the WH would allow a model to be released in their name saying that deaths will more than double, or that 100k lives can be saved if everyone wears a damn mask.

While the media stuff might be fear porn as you call it, I think it is important to drive all of this home. When attention to it waned, things blew up. Now the northern states will start going indoors more, while areas in the South that scaled back openings are now opening back up. Add schools/colleges starting back up, and there's definitely a recipe for spikes again.

It fucking sucks, and there are things I don't feel safe doing (more for the sake of others in high risk categories than myself), which tears me apart. Now and then there are very sobering stories or numbers like these that reaffirms my gut feeling that I'm doing the right thing.
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Post by Rocinante on 2020-09-04, 13:16

My kid already has a cold this school year. It’s amazing how different my wife and I react to it now. It really is just a cold, but it causes a lot more stress. She’s a 6th grader and already a kid has been diagnosed with C-19 and he and a bunch of traced contacts got sent home. This whole thing is so fucked.
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Post by WhiteBoyHatcher on 2020-09-04, 13:38

Neutral
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Post by Motown Spartan on 2020-09-04, 13:39

Rocinante wrote:My kid already has a cold this school year. It’s amazing how different my wife and I react to it now. It really is just a cold, but it causes a lot more stress. She’s a 6th grader and already a kid has been diagnosed with C-19 and he and a bunch of traced contacts got sent home. This whole thing is so fucked.

My daughter starts 6th grade on Tuesday. It’s all fucked right now.
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Post by MiamiSpartan on 2020-09-04, 14:52

Rocinante wrote:My kid already has a cold this school year. It’s amazing how different my wife and I react to it now. It really is just a cold, but it causes a lot more stress. She’s a 6th grader and already a kid has been diagnosed with C-19 and he and a bunch of traced contacts got sent home. This whole thing is so fucked.


Does the school require masks, have social distancing, and other mitigation measures in place? Seems like those should defend against colds, as well.
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Post by Rocinante on 2020-09-04, 15:17

Yeah they do. But there are spaces where they take them off. Gym when they are changing. The lunch room.
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Post by Rocinante on 2020-09-04, 15:19

Plus we have a 2 year old who goes to daycare, so....
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Post by Dendrobates on 2020-09-04, 15:28

Motown Spartan wrote:
Rocinante wrote:My kid already has a cold this school year. It’s amazing how different my wife and I react to it now. It really is just a cold, but it causes a lot more stress. She’s a 6th grader and already a kid has been diagnosed with C-19 and he and a bunch of traced contacts got sent home. This whole thing is so fucked.

My daughter starts 6th grade on Tuesday. It’s all fucked right now.

Thread hijack here... but how the hell is your kid in 6th grade already?!
Shocked
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Post by Motown Spartan on 2020-09-04, 15:33

Dendrobates wrote:
Motown Spartan wrote:

My daughter starts 6th grade on Tuesday. It’s all fucked right now.

Thread hijack here... but how the hell is your kid in 6th grade already?!
Shocked

No shit, right? She’s as tall as my wife!
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Post by tGreenWay on 2020-09-08, 20:00

Major phase 3 vaccine study by AstraZeneca has been put on pause because of a serious reaction by one of the patients. It’s not uncommon for something like this to happen in Phase 3.

https://www.statnews.com/2020/09/08/astrazeneca-covid-19-vaccine-study-put-on-hold-due-to-suspected-adverse-reaction-in-participant-in-the-u-k/
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Post by Dendrobates on 2020-09-08, 20:09

tGreenWay wrote:Major phase 3 vaccine study by AstraZeneca has been put on pause because of a serious reaction by one of the patients. It’s not uncommon for something like this to happen in Phase 3.

https://www.statnews.com/2020/09/08/astrazeneca-covid-19-vaccine-study-put-on-hold-due-to-suspected-adverse-reaction-in-participant-in-the-u-k/

It really is hard to say this early in the game. There will be some people who have serious reactions to a vaccine. Does that mean it’s common? That’s the question. And hence why it takes so damn long for drugs to come to market.

I wanted to throat punch Trump for saying it would be out before the election. Fucking idiot.
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Post by tGreenWay on 2020-09-08, 23:05

Dendrobates wrote:
tGreenWay wrote:Major phase 3 vaccine study by AstraZeneca has been put on pause because of a serious reaction by one of the patients. It’s not uncommon for something like this to happen in Phase 3.

https://www.statnews.com/2020/09/08/astrazeneca-covid-19-vaccine-study-put-on-hold-due-to-suspected-adverse-reaction-in-participant-in-the-u-k/

It really is hard to say this early in the game. There will be some people who have serious reactions to a vaccine. Does that mean it’s common? That’s the question. And hence why it takes so damn long for drugs to come to market.

I wanted to throat punch Trump for saying it would be out before the election. Fucking idiot.


Agreed, especially with a population as large as a Phase 3 trial typically is. Things happen. It just depends how often the same things happen to those getting the vaccine.
Trump’s comments aside, it was reassuring when a number of the companies signed an agreement to only release their products once they were deemed safe. Considering how the president has been attacking Big Pharma, including in his re-election ads, I don’t see many companies hurrying things along to satisfy his desire to have something before 11/3.
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Post by Robert J Sakimano on 2020-09-09, 06:26

tGreenWay wrote:Major phase 3 vaccine study by AstraZeneca has been put on pause because of a serious reaction by one of the patients. It’s not uncommon for something like this to happen in Phase 3.

https://www.statnews.com/2020/09/08/astrazeneca-covid-19-vaccine-study-put-on-hold-due-to-suspected-adverse-reaction-in-participant-in-the-u-k/
Coronavirus?? We gone?   - Page 18 502811600
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Post by Dendrobates on 2020-09-09, 10:31

I know my company has been working on a vaccine too. But they’ve really been on the DL publicly about it. We get some random vague updates saying it’s going well. Whatever that means. But I know and am glad these companies have agreed to not release them unless they feel them safe (and hopefully effective). I say hopefully, because we all know they are still going to push them out earlier than usual.
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Post by Robert J Sakimano on 2020-09-09, 10:51

I want my vaccine (sugar water concoction) to come with one (1) free ride on the Trump Amusement Park and Bible College water slide... the kind where they say a prayer for you before they push you down.

maybe at the bottom, as they're injecting me with a blueberry swish-flavored sugar solution, they could hand me a can of CheezWhiz and a package of bite-sized meat stix..

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Post by Robert J Sakimano on 2020-09-14, 15:35

not sure where else to put this, but Ingham County is done fuckin' around with the idiots.


EAST LANSING, Mich. – The Ingham County Health Department has identified 30 large houses in East Lansing with known exposure to coronavirus disease 2019 (COVID-19). People living in these properties have been ordered to quarantine immediately for the next two weeks.

The quarantine was mandated by an emergency order (Ingham 2020-18) issued by Ingham County Health Officer Linda S. Vail this afternoon. The quarantined properties include 23 fraternity and sorority house and seven large rental houses.

Consistent with MCL 333.2261 and 764.15(1), willful violation of this order constitutes a misdemeanor punishable by imprisonment for not more than 6 months, or a fine of not more than $200, or both. An individual may be arrested if violation occurs in the presence of a police officer, or the police officer has reasonable cause to believe individual has violated a rule or order.
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Post by tGreenWay on 2020-09-15, 00:42

Scientists at the University of Pittsburgh have identified a biomolecule that has shown to neutralize SARS CoV 2. They hope it can lead to preventative and therapeutic treatment in humans.

https://pittsburgh.cbslocal.com/2020/09/14/pitt-scientists-discover-biomolecule-that-may-neutralize-coronavirus/amp/
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Post by WhiteBoyHatcher on 2020-09-15, 00:45

That's awesome. But unfortunately if it's a new treatment... We are looking at a 2-3 year ramp up window unless I'm missing something. Which is totally possible.
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Post by tGreenWay on 2020-09-15, 00:47

WhiteBoyHatcher wrote:That's awesome. But unfortunately if it's a new treatment... We are looking at a 2-3 year ramp up window unless I'm missing something. Which is totally possible.


Yeah, I suspect we’ll need Dendro to lay out a timeline for us.
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Post by Dendrobates on 2020-09-15, 09:44

tGreenWay wrote:
WhiteBoyHatcher wrote:That's awesome. But unfortunately if it's a new treatment... We are looking at a 2-3 year ramp up window unless I'm missing something. Which is totally possible.


Yeah, I suspect we’ll need Dendro to lay out a timeline for us.

Timelines for drugs can be all over the place. And what is defined as the timeline: from synthesiation of the drug Or to pre-clinical trials? But average drugs (assuming it’s brand new and not indicated for anything else) is around 10-14 years. Now if you get an orphan drug fast track approval (which means a rare disease drug), it substantially speeds it up. You can skip phase 1, and even combine phases 2 and 3. So orphan drug status could come to market in 3-5 years.

I would imagine something like this would get approved as a fast track status like it is for orphan drugs.

If a drug is already to market, but research has shown it can be used for another indication, than you could probably get that to market in 3-5 years as well.

These are very general timelines, and you see timelines all over the place. Often times in the synthesis and purification stage could take many years before it moves to pre-clinical trials. And any other funding issues, patient population, and side effect issues can really prolong the process as well.

Think about this as well. 5 out of 5000 drugs actually make it to pre-clinical trials. Of those 5, 1 is tested on people. So 1 in 5000 drugs comes to market (in the US, which has the strictest FDA guidelines out of anywhere).
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Post by Robert J Sakimano on 2020-09-15, 10:09

Dendrobates wrote:
tGreenWay wrote:


Yeah, I suspect we’ll need Dendro to lay out a timeline for us.

Timelines for drugs can be all over the place. And what is defined as the timeline: from synthesiation of the drug Or to pre-clinical trials? But average drugs (assuming it’s brand new and not indicated for anything else) is around 10-14 years. Now if you get an orphan drug fast track approval (which means a rare disease drug), it substantially speeds it up. You can skip phase 1, and even combine phases 2 and 3. So orphan drug status could come to market in 3-5 years.

I would imagine something like this would get approved as a fast track status like it is for orphan drugs.

If a drug is already to market, but research has shown it can be used for another indication, than you could probably get that to market in 3-5 years as well.

These are very general timelines, and you see timelines all over the place. Often times in the synthesis and purification stage could take many years before it moves to pre-clinical trials. And any other funding issues, patient population, and side effect issues can really prolong the process as well.

Think about this as well. 5 out of 5000 drugs actually make it to pre-clinical trials. Of those 5, 1 is tested on people. So 1 in 5000 drugs comes to market (in the US, which has the strictest FDA guidelines out of anywhere).
I was told it would be ready the weekend before the election.

#MAGA
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Post by AvgMSUJoe on 2020-09-15, 14:16

Robert J Sakimano wrote:I was told it would be ready the weekend before the election.

#MAGA

"A very special day..."

The day Democracy officially died. Coronavirus?? We gone?   - Page 18 3836498553
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Post by Jake from State Farm on 2020-09-15, 15:02

AvgMSUJoe wrote:
Robert J Sakimano wrote:I was told it would be ready the weekend before the election.

#MAGA

"A very special day..."

The day Democracy officially died. Coronavirus?? We gone?   - Page 18 3836498553

Leonard Cohen was wrong.

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